真菌天然产物生物合成和真菌生物材料
卞光凯,博士,研究员。2017年于武汉大学获得生物化学与分子生物学博士学位。近5年来,在Nature,Nat. Catal.,Nat. Commun.,PNAS,JACS,Angew,Metab. Eng.等期刊上发表一作和通讯文章十余篇。主持国家自然科学基金青年及面上项目、承担科技部重点研发计划等科研项目。研究方向主要聚焦于天然产物生物合成与高产,真菌生物材料的理论及应用研究。
联系邮箱:gk.bian@siat.ac.cn
实验室主页:http://isynbio.siat.ac.cn/BianLab/
论文发表节选
Tao, H.#, Lauterbach, L.#, Bian, G.#, Chen, R.#, Hou, A.#, Mori, T.#, Cheng, S., Hu, B., Lu, L., Mu, X., Adachi, N., Kawasaki, M., Moriya, T., Senda, T., Wang, X., Deng, Z., Abe, I.*, Dickschat, J. S.*, Liu, T.* (2022), Discovery of non-squalene triterpenes. Nature, 2022, 606, 414-419. (IF: 49.962, 共一作)
Yuan, Y.#, Cheng, S.#, Bian, G.#, Yan, P., Ma, Z., Dai, W., Chen, R., Fu, S., Huang, H., Chi, H., Cai, Y., Deng, Z., Liu, T.* (2022), Efficient exploration of terpenoid biosynthetic gene cluster in filamentous fungi. Nature Catalysis, 5, 259–267. (IF: 41.813, 共一作)
Chen, R., Feng, T., Li, M., Zhang, X., He, J., Hu, B., Deng, Z., Liu, T., Liu, J.*, Wang, X.*, Bian, G.* (2022), Characterization of tremulane sesquiterpene synthase from basidiomycete Irpex lacteus. Organic Letters, 24, 5669−5673. (IF: 6.005, 主通讯).
Chen, R., Jia, Q., Mu, X., Hu, B., Sun, X., Deng, Z., Chen, F.*, Bian, G.*, Liu, T.* (2021), Systematic mining of fungal chimeric terpene synthases using an efficient precursor-providing yeast chassis. Proceedings of the National Academy of the Sciences, 118, 29, DOI, 10.1073/pnas.2023247118. (IF: 11.205, 共通讯)
He, H.#, Bian, G.#, Herbst-Gervasoni, C. J.#, Mori, T., Shinsky, S. A., Hou, A., Mu, X., Huang, M., Cheng, S., Deng, Z., Christianson, D. W.*, Abe, I.*, Liu, T.* (2020). Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases. Nature Communications, 11(1), 1-13. (IF: 14.919, 共一作)